
Lignans and related compounds
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Filtered Search Results

MEDCHEMEXPRESS LLC GBD-9
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NC2712610 GBD-9

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SELLECK CHEMICAL LLC ETOPOSIDE
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NC3522116 ETOPOSIDE

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Chemscene ChemScene | 9-Bromo-10-phenylanthracene | 25G | CS-W011944 | 0.98 | 23674-20-6| MFCD00230983 | 333.23
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ChemScene | 9-Bromo-10-phenylanthracene | 25G | CS-W011944 | 0.98 | 23674-20-6| MFCD00230983 | 333.23

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Sigma Organic Chemistry Rubrene | 1G | 517-51-1 | MFCD00003703 | 99.99% trace metals basis
Rubrene, 1G
About This Item:
Storage: room temp
EINECS Number: 208-242-0

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Selleck Chemical LLC Etoposide S1225-10g
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Etoposide is a semisynthetic derivative of podophyllotoxin which inhibits DNA synthesis via topoisomerase II inhibition activity which enhances double-strand and single-strand cleavage of DNA and reversibly inhibits repair by topoisomerase II binding Etoposide induces autophagy mitophagy and apoptosis

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Selleck Chemical LLC O-Demethyl-Gefitinib-E0833-5MG
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O-Desmethyl gefitinib a major active metabolite of gefitinib is a potent EGFR (ErbB1/HER1) inhibitor inhibits subcellular EGFR tyrosine kinase through a mechanism similar to that of gefitinib with IC50 values of 36 and 22 nM respectively

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Cayman Chemical EtoposIde-d3 1mg
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An inhibitor of IDO1 and TDO (IC50s 79 and 25 nM respectively in cell-free assays) decreases kynurenine levels in cells expressing human IDO1 (EC50 83 nM) decreases the percentage of PD-1 anti-CD3- and anti-CD28-activated Jurkat T cells from 0.025-1 UM decreases tumor volume and weight and the percentage of intratumoral CD4 CD25 Tregs in a B16/F10 murine melanoma model at 100 mg/kg when administered alone or in combination with paclitaxel

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AdipoGen Podophyllotoxin
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Chemical. CAS 518-28-5. Formula C22H22O8. MW 414.4. Isolated from Podophyllum emodi rhizomes. Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic.

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AdipoGen Podophyllotoxin
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Chemical. CAS 518-28-5. Formula C22H22O8. MW 414.4. Isolated from Podophyllum emodi rhizomes. Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic.

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Apexbio Technology LLC Etoposide 33419-42-0 10mM (in 1mL DMSO)
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Etoposide (VP-16) is a topoisomerase II inhibitor widely used in biomedical research to study mechanisms of DNA damage and cancer therapy It forms a stabilized complex with DNA and topoisomerase II preventing the enzyme-mediated religation of cleaved DNA strands Resulting DNA double-strand breaks lead to apoptosis particularly in rapidly dividing cancer cells Reported IC50 values vary across cell lines such as 59 2 M for topoisomerase II inhibition 30 16 M in HepG2 and 0 051 M for MOLT-3 indicating differential cytotoxic responses to etoposide in various cancer cell models

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Pfanstiehl Inc Podophyllotoxin (P-126) 5g pack API, active pharmaceutical ingredient CAS: 518-28-5
Podophyllotoxin (P-126) 5g pack API, active pharmaceutical ingredient CAS: 518-28-5

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Sigma Aldrich Fine Chemicals Biosciences Etoposide | 33419-42-0 | MFCD00869325 | 25 mg
Etoposide | Purity: 98.0-105.0% | Mol Wt: 588.56 | 33419-42-0 | MFCD00869325 | 25 mg

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eMolecules Ambeed / 910-Diphenylanthracene / 1g / 525149951 / A244724 / / 1499-10-1 / MFCD00001253 / 330.430 / C26H18
Ambeed / 910-Diphenylanthracene / 1g / 525149951 / A244724 / / 1499-10-1 / MFCD00001253 / 330.430 / C26H18

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Abcam Picropodophylloto x in, IGF-1R inhibitor, 5MG
MW 414.4 Da, Purity >97%. Selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Reduces pAkt and pErk1/2. Does not compete with ATP and may inhibit IGF-1R autophosphorylation. Anticancer agent. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement

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Pfanstiehl Inc Podophyllotoxin (P-126) 100g pack API, active pharmaceutical ingredient CAS: 518-28-5
Podophyllotoxin (P-126) 100g pack API, active pharmaceutical ingredient CAS: 518-28-5

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